| 1 |  Nairo Alexander Quintana Rojas (COL) | Movistar | 3:57:19 |
| 2 | Iván Ramiro Sosa Cuervo (COL) | Team Ineos | 0:08 |
| 3 | Miguel Angel López Moreno (COL) | Astana | 0:08 |
| 4 | Egan Arley Bernal Gomez (COL) | Team Ineos | 0:16 |
| 5 | Rigoberto Uran Uran (COL) | EF Education First | 1:01 |
| 6 | Daniel Felipe Martínez Poveda (COL) | EF Education First | 1:01 |
| 7 | Jhojan Orlando García Sosa (COL) | Manzana - Postobon | 1:27 |
| 8 | Didier Alonso Chaparro Lopez (COL) | Orgullo Paisa | 1:32 |
| 9 | Sergio Luis Henao Montoya (COL) | Uae Team Emirates | 1:36 |
| 10 |  Jhonnatan Manuel Narváez Prado (ECU) | Team Ineos | 1:40 |
| 11 | Winner Andrew Anacona Gomez (COL) | Movistar | 1:40 |
| 12 | Rodrigo Contreras Pinzón (COL) | Astana | 1:46 |
| 13 | Alejandro Osorio Carvajal (COL) | Nippo - Vini Fantini - Faizanè | 2:00 |
| 14 | Miguel Eduardo Florez Lopez (COL) | Androni Giocattoli - Sidermec | 2:00 |
| 15 | Freddy Emir Montaña Cadena (COL) | Epm | 2:00 |
| 16 |  Julian Alaphilippe (FRA) | Deceuninck - Quick Step | 2:00 |
| 17 | Jorge Camillo Castiblanco Cubides (COL) | Team Illuminate | 2:07 |
| 18 |  Matteo Badilatti (SUI) | Israel Cycling Academy | 2:14 |
| 19 | Danny Alberto Osorio Calle (COL) | Orgullo Paisa | 2:17 |
| 20 | Richard Antonio Carapaz Montenegro (ECU) | Movistar | 2:18 |
| 21 | Eduard Alexander Beltrán Suarez (COL) | Medellin | 2:18 |
| 22 | Óscar Adalberto Quiroz Ayala (COL) | Coldeportes - Bicicletas Strongman | 2:18 |
| 23 | Jefferson Albeiro Cepeda Hernandez (ECU) | Caja Rural - Seguros Rga Amateurs | 2:23 |
| 24 | Byron Patricio Guamá de la Cruz (ECU) | Movistar Ecuador | 2:31 |
| 25 | Brayan Hernandez Gomez (COL) | Coldeportes - Bicicletas Strongman | 2:34 |
| 26 |  Alex Hoehn (USA) | Aevolo | 2:38 |
| 27 | Harold Alfonso Tejada Canacue (COL) | Medellin | 2:51 |
| 28 |  Kevin Rivera Serrano (CRC) | Androni Giocattoli - Sidermec | 2:53 |
| 29 | Angel Alexander Gil Sanchez (COL) | Epm | 2:58 |
| 30 | Sebastián Alexander Castaño Muñoz (COL) | Beltrami Tsa - Hopplà - Petroli Firenze | 3:10 |
| 31 | Cristian Camilo Muñoz Lancheros (COL) | Uae Team Emirates | 3:19 |
| 32 |  Óscar Sevilla Rivera (ESP) | Medellin | 3:21 |
| 33 | Gregory Lawson Craddock (USA) | EF Education First | 3:21 |
| 34 | Dayer Quintana Rojas (COL) | Tharcor (ktm / Wilier Triestina - Selle Italia) | 3:59 |
| 35 | Daniel Felipe Muñoz Giraldo (COL) | Androni Giocattoli - Sidermec | 4:02 |
| 36 | Wilmar Jair Perez Muñoz (COL) | Deprisa Team | 4:03 |
| 37 | Johnatan Cañaveral Vargas (COL) | Coldeportes - Bicicletas Strongman | 4:03 |
| 38 |  Enrico Barbin (ITA) | Bardiani Valvole - CSF Inox | 4:18 |
| 39 | Nathan Brown (USA) | EF Education First | 4:55 |
| 40 | Anthony Rappo (SUI) | Iam - Excelsior | 4:55 |
| 41 | Julio Alexis Camacho Bernal (COL) | Coldeportes - Zenu | 5:06 |
| 42 | Fabio Andres Duarte Arevalo (COL) | Medellin | 5:06 |
| 43 | Einer Augusto Rubio Reyes (COL) | | 5:06 |
| 44 | Brayan Stiven Sanchez Vergara (COL) | Orgullo Paisa | 5:06 |
| 45 | Javier Ignacio Montoya Montoya (COL) | Beltrami Tsa - Hopplà - Petroli Firenze | 6:09 |
| 46 | Germán Enrique Cháves Torres (COL) | Coldeportes - Zenu | 6:11 |
| 47 | Aldemar Reyes Ortega (COL) | Manzana - Postobon | 6:24 |
| 48 | Brayan Stiven Ramirez Chacon (COL) | Coldeportes - Zenu | 6:26 |
| 49 | Miguel Angel Rubiano Chavez (COL) | Coldeportes - Zenu | 6:26 |
| 50 |  Jan Hirt (CZE) | Astana | 6:39 |
| 51 | Alvaro Raul Duarte Sandoval (COL) | | 7:09 |
| 52 | Edward Anderson (USA) | Hagens Berman - Axeon | 7:27 |
| 53 | Cameron Piper (USA) | Team Illuminate | 7:27 |
| 54 | Daniel Alexander Jaramillo Diez (COL) | Manzana - Postobon | 7:27 |
| 55 | Sebastián Henao Gómez (COL) | Team Ineos | 7:27 |
| 56 | Didier Alexander Sastoque Pulido (COL) | Betplay Cycling Team | 7:27 |
| 57 |  Bob Jungels (LUX) | Deceuninck - Quick Step | 7:27 |
| 58 | Joab Schneiter (SUI) | Iam - Excelsior | 7:27 |
| 59 | Edwin Andres Carvajal Jaramillo (COL) | Epm | 7:27 |
| 60 |  Sebastian Schönberger (AUT) | Tharcor (ktm / Wilier Triestina - Selle Italia) | 7:43 |
| 61 | Juan Pablo Suarez Suarez (COL) | GW - Shimano | 7:43 |
| 62 | Heiner Rodrigo Parra Bustamente (COL) | GW - Shimano | 7:43 |
| 63 |  Masakazu Ito (JAP) | Nippo - Vini Fantini - Faizanè | 7:47 |
| 64 | Rodolfo Andrés Torres Agudelo (COL) | Team Illuminate | 7:55 |
| 65 | Rafael Anibal Montiel Cuéllar (COL) | Orgullo Paisa | 7:55 |
| 66 | Jairo Alonso Cano Salas (COL) | Epm | 8:10 |
| 67 | Jorge Martín Montenegro Adaro (ESP) | | 8:24 |
| 68 | Sean Quinn (USA) | Hagens Berman - Axeon | 8:33 |
| 69 | Juan Esteban Arango Carvajal (COL) | | 8:45 |
| 70 | Norberto Wilches Rodriguez (COL) | Betplay Cycling Team | 8:47 |
| 71 | Luis Felipe Laverde Jimenez (COL) | GW - Shimano | 8:51 |
| 72 | Sebastián Orlando Caro Monroy (COL) | Deprisa Team | 8:51 |
| 73 | Juan Felipe Osorio Arboleda (COL) | Manzana - Postobon | 9:15 |
| 74 | Esteban David Villareal Almeida (ECU) | | 9:15 |
| 75 | Marcos Jurado Rodriguez (ESP) | Efapel Cycling | 9:30 |
| 76 | José Rodolfo Serpa Pérez (COL) | GW - Shimano | 9:58 |
| 77 | Edison Muñoz Lopez (COL) | Orgullo Paisa | 10:00 |
| 78 | Jose Nicolas Castro Laverde (COL) | GW - Shimano | 10:15 |
| 79 | Marc Soler Gimenez (ESP) | Movistar | 11:19 |
| 80 | Jorge Arcas Peña (ESP) | Movistar | 11:19 |
| 81 | Simon Pellaud (SUI) | Iam - Excelsior | 11:19 |
| 82 | Antoine Debons (SUI) | Iam - Excelsior | 11:19 |
| 83 | Diego Antonio Ochoa Camargo (COL) | Manzana - Postobon | 11:19 |
| 84 | Alex Howes (USA) | EF Education First | 11:19 |
| 85 |  João Pedro Almeida Gonçalves (POR) | Hagens Berman - Axeon | 11:56 |
| 86 |  Etienne Van Empel (NED) | Tharcor (ktm / Wilier Triestina - Selle Italia) | 12:38 |
| 87 | Gabriel Francisco Rojas Campos (CRC) | Aevolo | 13:02 |
| 88 | Davide Villella (ITA) | Astana | 13:28 |
| 89 |  Nikita Stalnov (KAZ) | Astana | 13:28 |
| 90 | Hernando Bohorquez Sanchez (COL) | Astana | 13:28 |
| 91 | Sierra Elkin Sebastian Palmar (COL) | | 13:28 |
| 92 | Edwin Alcibiades Avila Vanegas (COL) | Israel Cycling Academy | 13:38 |
| 93 | Jaime Alberto Castañeda Ortega (COL) | Epm | 13:38 |
| 94 | Samuele Zoccarato (ITA) | Iam - Excelsior | 13:53 |
| 95 | Cristian David Pita Bolaños (ECU) | Movistar Ecuador | 14:09 |
| 96 | Nicolas Jonathan Castroviejo (ESP) | Team Ineos | 14:16 |
| 97 |  Chris Froome (GBR) | Team Ineos | 14:16 |
| 98 | Juan Diego Alba Bolivar (COL) | Coldeportes - Zenu | 14:16 |
| 99 | Janier Alexis Acevedo Calle (COL) | Epm | 14:16 |
| 100 | Rubén Darío Acosta Ospina (COL) | Nippo - Vini Fantini - Faizanè | 14:16 |
| 101 | Mirco Maestri (ITA) | Bardiani Valvole - CSF Inox | 14:45 |
| 102 | Jose Tito Hernandez Jaramillo (COL) | Orgullo Paisa | 14:45 |
| 103 |  Fabricio Ferrari Barcelo (URU) | Efapel Cycling | 15:18 |
| 104 | Lorenzo Fortunato (ITA) | Tharcor (ktm / Wilier Triestina - Selle Italia) | 15:28 |
| 105 |  Eduardo Sepúlveda (ARG) | Movistar | 16:16 |
| 106 | Rafael Jorge Magalhães Silva (POR) | Efapel Cycling | 16:16 |
| 107 | William David Muñoz Perez (COL) | Coldeportes - Bicicletas Strongman | 16:18 |
| 108 | Marco Maronese (ITA) | Bardiani Valvole - CSF Inox | 16:29 |
| 109 | Dario Puccioni (ITA) | Sangemini - Trevigiani - Mg.kvis | 16:36 |
| 110 | Diego Fernando Ruiz Rojas (COL) | Betplay Cycling Team | 16:43 |
| 111 | Marvin Angarita Reyes (COL) | | 18:19 |
| 112 | Alex Alberto Cano Ardila (COL) | Coldeportes - Zenu | 19:18 |
| 113 | Juan Sebastián Molano Benavides (COL) | Uae Team Emirates | 19:18 |
| 114 | Aristobulo Cala Cala (COL) | Coldeportes - Bicicletas Strongman | 19:18 |
| 115 | Eduardo Estrada Celis (COL) | Coldeportes - Bicicletas Strongman | 19:18 |
| 116 | Steven Manuel Cuesta Zamora (COL) | Deprisa Team | 19:18 |
| 117 | Cristián Torres Cuenca (COL) | | 19:18 |
| 118 | Cole Davis (USA) | Hagens Berman - Axeon | 19:18 |
| 119 | Petr Vakoc (CZE) | Deceuninck - Quick Step | 21:56 |
| 120 | Daniel Turek (CZE) | Israel Cycling Academy | 21:56 |
| 121 | Davide Baldaccini (ITA) | Team Colpack | 21:56 |
| 122 | Clément Carisey (FRA) | Israel Cycling Academy | 21:56 |
| 123 | Paolo Simion (ITA) | Bardiani Valvole - CSF Inox | 22:05 |
| 124 | Oliviero Troia (ITA) | Uae Team Emirates | 24:00 |
| 125 | Alvaro José Hodeg Chagui (COL) | Deceuninck - Quick Step | 24:00 |
| 126 | Imerio Cima (ITA) | Nippo - Vini Fantini - Faizanè | 24:00 |
| 127 | Luca Pacioni (ITA) | Tharcor (ktm / Wilier Triestina - Selle Italia) | 24:00 |
| 128 | Tom Bohli (SUI) | Uae Team Emirates | 24:00 |
| 129 | Taylor Phinney (USA) | EF Education First | 24:00 |
| 130 | Carlos Eduardo Alzate Escobar (COL) | GW - Shimano | 24:00 |
| 131 | Albeiro Rabon Vela (COL) | Deprisa Team | 24:00 |
| 132 | Wilmar Andrés Paredes Zapata (COL) | Manzana - Postobon | 24:00 |
| 133 | Weimar Alfonso Roldan Ortiz (COL) | Medellin | 24:00 |
| 134 | Walter Alejandro Vargas Alzate (COL) | Medellin | 24:00 |
| 135 |  Iljo Keisse (BEL) | Deceuninck - Quick Step | 26:53 |
| 136 | Ariel Maximiliano Richeze Araquistaín (ARG) | Deceuninck - Quick Step | 26:53 |
| DNS | Félix Alejandro Barón Castillo (COL) | Team Illuminate | - |
| DNS | Ivan Santaromita (ITA) | Nippo - Vini Fantini - Faizanè | - |
